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. 2022 Jan 28;5:102. doi: 10.1038/s42003-022-03035-2

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Pearson’s correlation of normalized H3K27ac signal around promoter regions (TSS ± 2 kb). b Tracks of normalized H3K27ac signal for replicates dosed with PBS, low-dose LPS, or high-dose LPS (from top to bottom). Tracks are aligned in mm10 and the region displayed is chr7:35,042,108-35,138,618. c Distribution of normalized H3K27ac signal at peaks (n = 29,071). The middle bar of the boxplot denotes the median. The upper and lower bounds of the box correspond to the 75th and 25th percentile, respectively. Each whisker spans up to the range of 1.5 * interquartile range from the edge of the box. d Number of peaks gained or lost in low-dose or high-dose conditions compared to PBS. e Percentage of peaks at genomic locations.