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. 2022 Jan 28;5:102. doi: 10.1038/s42003-022-03035-2

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Pearson’s correlation of RNA-seq signal between conditions. b Principle Component Analysis of replicates using top 500 variable genes. c Heatmap of WT and TRAM-deficient gene expression at varied LPS-dosage using DEGs from the WT comparisons. Significant pathways on right are from Gene Ontology or WikiPathways. Log(FDR) for each in parentheses.