Table 2.
Localisation and Immunostaining intensity of AnxA1 and Gal-3 expression in placental villous tissues
| AnxA1 | Gal-3 | ||||||
|---|---|---|---|---|---|---|---|
| SCORE | STM | CVSC | VVEC | STM | CVSC | VVEC | |
| Normal (n = 30) | 0 | 0 | 4 (13) | 4 (13) | 0 | 11 (36) | 9 (30) |
| 1+ | 7 (23) | 20 (66) | 21( 70) | 17 (56) | 14 (46) | 21 (70) | |
| 2+ | 21 (70) | 6 (20) | 5 (16) | 12 (40) | 5 (16) | 0 | |
| 3+ | 2 (6) | 0 | 0 | 1 (3) | 0 | 0 | |
| PE (n = 30) | 0 | 0 | 1 (3) | 1 (3) | 0 | 7 (23) | 7 (23) |
| 1+ | 0 | 7 (23) | 17 (56) | 7 (23) | 15 (50) | 20 (66) | |
| 2+ | 15 (50) | 22 (73) | 12 (40) | 14 (46) | 8 (26) | 3 (10) | |
| 3+ | 15 (50) | 0 | 0 | 9 (30) | 0 | 0 | |
| P value | 0.000* | 0.000* | 0.000* | 0.000* | 0.140 | 0.000* | |
Statistical analysis of expression of AnxA1 and Gal-3 for IHC was carried out with the Mann–Whitney U-test (*P < 0.05)
Immunohistochemical staining for AnxA1, 0 = no staining, 1–10% as 1+ , 11–50% as 2+ , 51–70% as 3+ , 71–100% as 4 + . (Numbers in bracket are in the percentage)
STM Syncytiotrophoblast membrane, CVSC chorionic villous stromal cells, VSMC vascular smooth muscle cell, VVEC villous vascular endothelial cells