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. 2021 Jan 12;37(1):60–68. doi: 10.1007/s12291-020-00952-z

Table 2.

Localisation and Immunostaining intensity of AnxA1 and Gal-3 expression in placental villous tissues

AnxA1 Gal-3
SCORE STM CVSC VVEC STM CVSC VVEC
Normal (n = 30) 0 0 4 (13) 4 (13) 0 11 (36) 9 (30)
1+ 7 (23) 20 (66) 21( 70) 17 (56) 14 (46) 21 (70)
2+ 21 (70) 6 (20) 5 (16) 12 (40) 5 (16) 0
3+ 2 (6) 0 0 1 (3) 0 0
PE (n = 30) 0 0 1 (3) 1 (3) 0 7 (23) 7 (23)
1+ 0 7 (23) 17 (56) 7 (23) 15 (50) 20 (66)
2+ 15 (50) 22 (73) 12 (40) 14 (46) 8 (26) 3 (10)
3+ 15 (50) 0 0 9 (30) 0 0
P value 0.000* 0.000* 0.000* 0.000* 0.140 0.000*

Statistical analysis of expression of AnxA1 and Gal-3 for IHC was carried out with the Mann–Whitney U-test (*P < 0.05)

Immunohistochemical staining for AnxA1, 0 = no staining, 1–10% as 1+ , 11–50% as 2+ , 51–70% as 3+ , 71–100% as 4 + . (Numbers in bracket are in the percentage)

STM Syncytiotrophoblast membrane, CVSC chorionic villous stromal cells, VSMC vascular smooth muscle cell, VVEC villous vascular endothelial cells