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. 2021 Jun 16;12(1):467–482. doi: 10.1016/j.apsb.2021.05.012

Figure 2.

Figure 2

Characterization of micelles and activated platelets-binding ability. (A) The preparation of DOX-loaded micelle FD/DOX. (B) The appearance, TEM image and particle size distribution of FD/DOX. Scale bar = 100 nm. (C) The preparation of DOX-loaded micelle DD/DOX. (D) The TEM image and particle size distribution of DD/DOX. Scale bar = 100 nm. (E) Fluorescent images of platelets with or without activation incubated separately with FD/DOX and DD/DOX for 20 min. Scale bar = 100 μm. (F) Flow Cytometer detection of the micelles bound to platelets with or without activation. Data are presented as mean ± SD (n = 3), ∗∗∗P < 0.001. (G) Flow Cytometer detection of FD/DOX bound to activated platelets with or without anti-CD62P antibody pre-incubation. Data are presented as mean ± SD (n = 3), ∗∗∗P < 0.001.