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. 2021 Jun 16;12(1):467–482. doi: 10.1016/j.apsb.2021.05.012

Figure 6.

Figure 6

Anti-tumor and anti-metastasis effect on 4T1 spontaneous metastasis model. (A) The diagram of 4T1 spontaneous metastasis model and the treatment. (B) Bioluminescence imaging of tumors and lung metastasis in tumor-bearing mice treated with Glu, Fu, DOX, DD/DOX or FD/DOX (DOX-equivalent 2.5 mg/kg), respectively (n = 3). (C) Semi-quantitative analysis of bioluminescence signal of tumor. Data are presented as mean ± SD (n = 3), ∗∗∗P < 0.001. (D) Semi-quantitative analysis of bioluminescence signal of lung metastasis. Data are presented as mean ± SD (n = 3), ∗∗P < 0.01, ∗∗∗P < 0.001. (E) Survival curve of 4T1 tumor-bearing mice treated with preparations (n = 10).