Table 3.
The relationship between DOK expression and drug sensitivity.
| Gene | Drug | correlation | p-value |
|---|---|---|---|
| DOK2 | Chelerythrine | 0.7085977 | 2.39E−10 |
| DOK6 | Estramustine | 0.5482401 | 5.77E−06 |
| DOK4 | okadaic acid | −0.488041 | 7.64E−05 |
| DOK2 | Pipobroman | 0.4788433 | 0.0001087 |
| DOK2 | Idarubicin | 0.4686688 | 0.0001589 |
| DOK4 | Carfilzomib | −0.466327 | 0.0001731 |
| DOK2 | Uracil mustard | 0.4610959 | 0.0002091 |
| DOK2 | Melphalan | 0.4607304 | 0.0002119 |
| DOK2 | Dimethylaminoparthenolide | 0.4603258 | 0.000215 |
| DOK6 | Nelfinavir | 0.4600371 | 0.0002172 |
| DOK6 | Etoposide | 0.4585132 | 0.0002293 |
| DOK4 | Depsipeptide | −0.458461 | 0.0002298 |
| DOK4 | Pipamperone | −0.457402 | 0.0002386 |
| DOK2 | Carmustine | 0.4488611 | 0.0003217 |
| DOK4 | Paclitaxel | −0.447562 | 0.0003365 |
| DOK3 | kahalide f | −0.44348 | 0.0003868 |
| DOK2 | Fludarabine | 0.4415362 | 0.0004132 |
| DOK2 | Thiotepa | 0.440709 | 0.0004249 |
| DOK6 | Carmustine | 0.4405261 | 0.0004275 |
| DOK2 | Carboplatin | 0.4359063 | 0.0004989 |
| DOK2 | Asparaginase | 0.4344543 | 0.0005235 |
| DOK2 | Arsenic trioxide | 0.4304928 | 0.0005962 |
| DOK2 | PX-316 | 0.4280999 | 0.0006445 |
| DOK4 | Eribulin mesilate | −0.426006 | 0.0006896 |
| DOK4 | Vinblastine | −0.425417 | 0.0007028 |
| DOK6 | 7-Hydroxystaurosporine | 0.4248457 | 0.0007158 |
| DOK4 | Actinomycin D | −0.420248 | 0.0008288 |
| DOK2 | Etoposide | 0.4176907 | 0.0008984 |
| DOK2 | Ifosfamide | 0.4162463 | 0.00094 |
| DOK2 | Triethylenemelamine | 0.4146959 | 0.0009865 |
| DOK1 | Gemcitabine | 0.4113606 | 0.0010938 |
| DOK6 | Megestrol acetate | 0.4074377 | 0.0012334 |
| DOK4 | Vinorelbine | −0.400945 | 0.0014998 |
| DOK4 | Dolastatin 10 | −0.394018 | 0.00184 |
| DOK6 | Salinomycin | 0.3939486 | 0.0018438 |
| DOK6 | Teniposide | 0.3923908 | 0.0019293 |
| DOK6 | AP-26113 | 0.3909877 | 0.0020094 |
| DOK2 | Parthenolide | 0.3900241 | 0.0020661 |
| DOK6 | Ethinyl estradiol | 0.3855035 | 0.0023517 |
| DOK2 | Lomustine | 0.3831947 | 0.0025107 |
| DOK6 | Arsenic trioxide | 0.3824409 | 0.0025647 |
| DOK6 | Epirubicin | 0.3809366 | 0.0026755 |
| DOK2 | Nitrogen mustard | 0.3794911 | 0.0027859 |
| DOK2 | Digoxin | 0.3773697 | 0.0029553 |
| DOK2 | Cytarabine | 0.3771083 | 0.0029768 |
| DOK7 | Pipamperone | −0.375646 | 0.0030997 |
| DOK6 | Isotretinoin | 0.3743589 | 0.0032115 |
| DOK2 | XK-469 | 0.3682948 | 0.0037879 |
| DOK7 | BN-2629 | −0.365256 | 0.0041097 |
| DOK2 | Cisplatin | 0.3616868 | 0.0045185 |
| DOK6 | Irofulven | −0.359741 | 0.0047561 |
| DOK7 | Midostaurin | −0.359726 | 0.004758 |
| DOK1 | Triapine | 0.3589469 | 0.0048562 |
| DOK7 | Epirubicin | −0.358925 | 0.004859 |
| DOK1 | Triethylenemelamine | 0.357197 | 0.0050833 |
| DOK4 | Tyrothricin | −0.356618 | 0.0051605 |
| DOK2 | BN-2629 | 0.356401 | 0.0051897 |
| DOK3 | ABT-199 | 0.35528 | 0.0053428 |
| DOK1 | 5-fluoro deoxy uridine 10mer | 0.3537224 | 0.0055622 |
| DOK3 | Carboplatin | 0.3534247 | 0.005605 |
| DOK4 | Carmustine | −0.352144 | 0.0057926 |
| DOK4 | Arsenic trioxide | −0.351821 | 0.0058407 |
| DOK2 | Dexrazoxane | 0.3498989 | 0.0061345 |
| DOK1 | Asparaginase | 0.3494209 | 0.0062096 |
| DOK6 | Ifosfamide | 0.3484718 | 0.006361 |
| DOK1 | LMP-400 | 0.3483937 | 0.0063736 |
| DOK1 | Thiotepa | 0.3474983 | 0.0065197 |
| DOK2 | Cladribine | 0.3462837 | 0.0067225 |
| DOK2 | Batracylin | 0.3459751 | 0.0067749 |
| DOK7 | Bortezomib | −0.344944 | 0.0069526 |
| DOK1 | Cladribine | 0.34487 | 0.0069655 |
| DOK4 | Lomustine | −0.342182 | 0.0074488 |
| DOK7 | Carmustine | −0.341285 | 0.0076165 |
| DOK4 | Mithramycin | −0.340635 | 0.0077401 |
| DOK2 | Calusterone | 0.3405351 | 0.0077592 |
| DOK4 | Ethinyl estradiol | −0.340444 | 0.0077768 |
| DOK1 | Uracil mustard | 0.3401498 | 0.0078335 |
| DOK2 | Teniposide | 0.3400573 | 0.0078514 |