Scheme 2.
Reagents and conditions: (h) MgSO4, NaBH4, MeOH, rt, overnight; (i) γ-butyro-lactone, trimethylaluminum, toluene, 80 °C, 12 h; (j) DMP, DCM, rt, 2 h; (j) 18, MgSO4, NaBH4, MeOH, rt, overnight.
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