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. 2021 Jun 2;12(1):107–134. doi: 10.1016/j.apsb.2021.05.031

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© 2022 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Gold nanoparticles in situ generated in B16F10 and DCs for the combination of PPT and immunotherapy. (A) Schematic of construction and immunological functions of AUNP@DC_B16F10. (B) TEM images of AUNP@DC_B16F10. (C) temperature change (ΔT) of AuNP, AuNP@DC_L929, and AuNP@DC_B16F10. (D) images presenting live/dead cells after treatment with AuNP@DC_B16F10 or/and laser. (E) primary tumor volume following the indicated treatment. (F) distant tumor weight following the indicated treatment. (G) DC maturation following the indicated treatment. (H) CD4⁺ T cell count after the indicated treatment. Reprinted with the permission from Ref. 161. Copyright © 2019 ACS Publishing Group.