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. 2021 Jul 17;12(1):308–315. doi: 10.1016/j.apsb.2021.07.007

Figure 4.

Figure 4

In vitro [18F]MAGL-4-11 autoradiographic and MAGL immunofluorescent analysis of liver sections from CCl4 and BDL mice. (A) Representative autoradiogram of [18F]MAGL-4-11 and double immunohistochemistry of MAGL (red) and α-SMA (green) in CCl4 liver sections. (B) Representative autoradiographic [18F]MAGL-4-11 images and double immunohistochemistry of MAGL (red) and α-SMA (green) in BDL liver sections. (C) Radioactivity and MAGL fluorescence intensity in CCl4 and BDL mice liver sections. Graph represents mean ± SEM. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001, n = 3 animal/group. (D) Correlation between MAGL expression and [18F]MAGL-4-11 uptake in CCl4 and BDL mice liver sections, n = three animal/group.