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. 2021 Jun 4;190(11):2453–2460. doi: 10.1093/aje/kwab170

Figure 1.

Figure 1

Causal directed acyclic graph corresponding to target trial 1. For each surgeon, Inline graphic is operative volume during interval Inline graphic, Lk is a vector of covariates during Inline graphic (e.g., surgeon characteristics, average patient characteristics, average hospital characteristics, and mortality risk), Inline graphic is operative volume during Inline graphic (under full adherence to assignment), Inline graphic is the 90-day mortality risk of patients who underwent an operation during Inline graphic, and U is a vector of unmeasured covariates. Directed edges between Inline graphic, Lk, and Inline graphic are omitted for simplification.