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. 2021 Jun 4;190(11):2453–2460. doi: 10.1093/aje/kwab170

Figure 2.

Figure 2

Causal directed acyclic graph corresponding to target trial 2. For each surgeon, Inline graphic is operative volume during interval Inline graphic; Lk is a vector of covariates during period Inline graphic (e.g., surgeon characteristics, average patient characteristics, average hospital characteristics, and mortality risk during the prior interval), with Inline graphic also including time-fixed surgeon and hospital covariates; Inline graphic is operative volume during period Inline graphic; Inline graphic is the 90-day mortality risk of patients who underwent an operation during interval Inline graphic; and U is a vector of unmeasured covariates. Directed edges between Inline graphic, Lk, and Inline graphic are omitted for simplification.