Fig. 5. Top 20 KEGG pathway enrichments in the lungs of pigs following infection with PRRSV or HPS alone or dual PRRSV-HPS infection, as well as DEGs of immune-related pathways from co-challenged pigs. (A) HPS challenged group; (B) PRRSV challenged group; (C) PRRSV and HPS co-challenged group; (D) The Circos plot of DEGs list in immune-related KEGG pathways from PRRSV-HPS group.

KEGG, Kyoto Encyclopedia of Genes and Genomes; PRRSV, porcine reproductive and respiratory syndrome virus; HPS, Haemophilus parasuis; DEG, differentially expressed gene.