Table 2.
Study outcomes: positive PCR tests and COVID-19.
| Bromhexine treatment group | Control group | Overall | P | ||
|---|---|---|---|---|---|
| n | 25 | 25 | 50 | 1.00 | |
| Primary outcome (positive PCR test or COVID-19) | 2 | 7 | 9 | 0.07 | |
| Positive SARS-CoV-2 PCR test, n | 2 | 7 | 9 | 0.07 | |
| Asymptomatic | 2 | 2 | 4 | 1.00 | |
| Symptomatic | 0 | 5 | 5 | 0.02 | |
| COVID-19 moderate, n | 0 | 3 | 3 | 0.08 | |
| COVID-19 severe with hospitalization, n | 0 | 2 | 2 | 0.16 | |
| Drug nonadherence | |||||
| Missed doses of bromhexine, n | 4 | — | — | — | |
| Number of missed bromhexine doses, median [IQR] | 6 [5.25; 7.5] | — | — | — | |
| Adverse events, n | 2 | 0 | 2 | 0.16 |
n, number of participants; IQR, interquartile range; PCR, polymerase chain reaction.