Table 1.
Clinical and demographic characteristics of hospitalized patients with CDI patients, stratified by mortality
| No death within 30 days, N (%) | Death within 30 days, N (%) | p value | |
|---|---|---|---|
| BMI | |||
| < 20 | 519 (14.9%) | 39 (10.5%) | 0.32 |
| 20–25 | 1175 (33.8%) | 135 (36.2%) | |
| 25–30 | 920 (26.5%) | 108 (29.0%) | |
| 30–35 | 490 (14.1%) | 49 (13.1%) | |
| 35–40 | 213 (6.1%) | 22 (5.9%) | |
| 40–45 | 92 (2.6%) | 10 (2.7%) | |
| > 45 | 69 (2.0%) | 10 (2.7%) | |
| Sex | |||
| Female | 1830 (52.6%) | 194 (52.0%) | 0.82 |
| Male | 1648 (47.4%) | 179 (48.0%) | |
| Age | |||
| 18–55 years | 1102 (31.7%) | 56 (15.0%) | < 0.01 |
| 56–75 years | 1522 (43.8%) | 180 (48.3%) | |
| ≥ 76 years | 854 (24.6%) | 137 (36.7%) | |
| Race/ethnicity | |||
| Black | 356 (10.2%) | 37 (9.9%) | 1.00 |
| Hispanic | 385 (11.1%) | 41 (11.0%) | |
| White | 1930 (55.5%) | 207 (55.5%) | |
| Other | 807 (23.2%) | 88 (23.6%) | |
| Charlson comorbidity index | |||
| 0–3 points | 1439 (41.4%) | 62 (16.6%) | < 0.01 |
| 4–6 points | 1682 (48.4%) | 249 (66.8%) | |
| > 7 points | 357 (10.3%) | 62 (16.6%) | |
| Vital signs | |||
| Temperature < 35, > 38 °C | 578 (24.7%) | 98 (41.0%) | < 0.01 |
| Heart rate > 100 beats/min | 1728 (56.5%) | 247 (77.4%) | < 0.01 |
| MAP < 65 mmHg | 940 (30.9%) | 193 (62.1%) | < 0.01 |
| Lab values | |||
| WBC count > 15 × 103/μL | 1100 (31.6%) | 208 (55.8%) | < 0.01 |
| Hematocrit < 37.2% | 2375 (91.2%) | 308 (96.9%) | < 0.01 |
| Platelet count < 156 × 103/μL | 1302 (37.4%) | 209 (56.0%) | < 0.01 |
| Total bilirubin > 1.3 mg/dL | 308 (14.0%) | 86 (33.1%) | < 0.01 |
| Albumin < 3 g/dL | 1306 (44.4%) | 241 (70.5%) | < 0.01 |
| Creatinine > 1.5 mg/dL | 1087 (31.4%) | 218 (58.4%) | < 0.01 |
| Hospitalization | |||
| Vasopressor use | 533 (15.3%) | 140 (37.5%) | < 0.01 |
| ICU stay | 914 (26.3%) | 208 (55.8%) | < 0.01 |
Baseline characteristics of patients with Clostridioides difficile infection (n = 3851), stratified based on death within 30 days
CDI, Clostridioides difficile infection; BMI, body mass index; MAP, mean arterial pressure; WBC, white blood cell; ICU, intensive care unit