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. 2021 May 15;12(1):424–436. doi: 10.1016/j.apsb.2021.05.003

Figure 2.

Figure 2

1H NMR spectrum of polyHPMA-SS-polyHPMA (recorded in d6-DMSO) (A), and 1H NMR spectra of the amphiphilic and block polymeric prodrug [polyDOX-block-(polyHPMA-SS-polyHPMA)-block-polyDOX] (solvent: d6-DMSO) (B). Size exclusion chromatogram (SEC) of the final prodrug (MW 93.5 kDa) (C), and its degraded low-MW segments (MW 41.2 kDa) (D). Characterization of NPs and NPs(Ce6) with size distribution from DLS (E), UV‒Vis absorption spectra (F); and TEM morphology of NPs (G) and NPs(Ce6) (H), scale bar: 50 nm.