Table 2.
The enrichment statistics of sirtuin signaling pathway in four DIA software
| Model | Software | pa | Ratiob | Z-scorec |
|---|---|---|---|---|
| Model IMA | OpenSWATH | 4.48 | 0.0825 | 1.155 |
| Model IMA | Spectronaut | 13.7 | 0.155 | 2.414 |
| Model IMA | DIA-NN | 8.97 | 0.134 | 2.449 |
| Model IMA | EncyclopeDIA | 20.6 | 0.251 | 3.202 |
| Model ADR | OpenSWATH | 9.87 | 0.144 | 2.4 |
| Model ADR | Spectronaut | 6.8 | 0.12 | 1 |
| Model ADR | DIA-NN | 21.8 | 0.296 | 1.336 |
| Model ADR | EncyclopeDIA | 9.31 | 0.155 | 3.138 |
a
p Value is the result of Fisher's exact test.
b
Ratio is the number of proteins from different DIA software that map to the pathway divided by the total number of proteins that map to the same pathway.
c
Z-score is calculated by the IPA z-score algorithm to predict the direction of change for the function. An absolute z-score of ≥2 is considered as significant.