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. 2021 Apr 27;74(2):263–270. doi: 10.1093/cid/ciab367

Table 2.

Care Delivery During Hospitalizations of Persons Who Use Drugs (PWUD) and Non-PWUD

Characteristic PWUD
(n = 372)
Non-PWUD
(n = 591)
P Value
Planned parenteral antibiotic treatment
 Bacteremia alone, median weeks (IQR) 4 (2–6) 4 (2–6) .59a
 Endocarditis, median weeks (IQR) 6 (6–6) 6 (6–6) .35a
 Vertebral osteomyelitis, median weeks (IQR) 6 (6–6) 6 (6–6) .63a
 Epidural abscess, median weeks (IQR) 6 (6–6) 6 (6–6) .43a
Inpatient medications for OUD (persons reporting opioid use, n = 214)
 New start methadone ≤40 mg 36 (17)
 New start methadone >40 mg 11 (5)
 New start buprenorphine 6 (3)
 Prior methadone or buprenorphine continued 63 (29)
 No inpatient treatment for OUD 98 (46)
Discharge planning
 PICC placedb 202/309 (65) 334/400 (84) <.001c
 Discharge setting <.001c
  Remained inpatient for antibiotic course 65 (18) 64 (11)
  Skilled nursing facility 157 (42) 194 (33)
  Home 48 (13) 208 (35)
  Patient-directed discharge from hospital 46 (12) 7 (1)
  Otherd 24 (6) 23 (4)
  Died or transitioned to hospice in the hospital 31 (8) 95 (16)
 Patient-directed discharge (“AMA”) any time during antibiotic coursee 80 (24) 12 (2) <.001c

Data are presented as No. (%) unless otherwise indicated.

Abbreviations: AMA, against medical advice; IQR, interquartile range; OUD, opioid use disorder; PICC, peripherally inserted central catheter.

a P value calculated using Wilcoxon rank-sum test.

bNot including those with preexisting central access, those who died, or those who transitioned to hospice in the hospital.

c P value calculated using χ 2 test.

dIncludes transfer back to referring hospital, discharge to medical respite (recuperative services for homeless persons), etc.

eDenominator in those who survived to hospital discharge, not on hospice: n = 340 in PWUD, n = 496 in non-PWUD.