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. 2021 May 4;74(2):227–236. doi: 10.1093/cid/ciab393

Table 1.

Routine and Influenza Vaccines Schedules, and Cold Storage Volume per Dose

Schedule Cold Storage Tertiary Packaging volume per dose (mL) Cold Storage Secondary Packaging Volume per dose (mL)
Routine infant immunization
 Bacille Calmette-Guerin Birth dose 4.98 1.44
 Hepatitis B Birth dose 12.56 2.86
 Diphtheria-tetanus-pertussis-hepatitis B-Haemophilus influenzae type b (pentavalent) 6, 10, and 14 weeks 16.70 3.06
 Polio (oral) 6, 10, and 14 weeks 6.22 1.40
 Polio (inactivated) 6 weeks 23.95 4.00
 Pneumococcal (conjugate) 6, 10, and 14 weeks 36.28 3.60
 Rotavirus 6 and 10 weeks 49.45 46.30
 Measles-rubella 9–12 months, 13–24 months 9.84 2.11
 Tetanus-diphtheria 13–24 months 9.47 2.38
Meningococcal A (conjugate) (African country only) 13–24 months 9.84 2.11
 Yellow fever (African country only) 9–12 months 3.59 2.99
Japanese encephalitis (South-East Asian country only) 9–12 months 39.4 4.2
Routine children immunization
 HPV4 (girls only) 2 doses from 9 to 14 years 7.61 4.84
 Tetanus-diphtheria 9–14 years 9.47 2.38
Influenza immunization
 Risk groups: children <5 years, pregnant women, ≥65 years, healthcare workers, chronic diseases 2 doses, 1 month apart for first year of life, and 1 dose annually thereafter 7.22 (multidose vial) 5.40 (multidose vial)
87.3 (single dose vial) 18.4 (single dose vial)
111.8 (prefilled syringe) 86.5 (prefilled syringe)

Vaccines and schedules are from World Health Organization (WHO) policy statements and immunization tables [1]. Tertiary and secondary packaging volumes per dose from WHO Prequalified Vaccines Database. Human papillomavirus (HPV) vaccination programs generally target girls only aged 9–14 years [18]. We assumed the full HPV immunization series was given to girls 9 years of age.