Fig. 2.

ILEI forms a protein complex with LIFR and activates LIFR A IHC analysis of LIFR renal expression in mice. B, C WB analyses of LIFR renal expression in mice, *p < 0.05. D–F LIFR overexpression efficiency in HK2 cells examined by WB and real-time PCR, *p < 0.05. G–I The expression level of LIFR examined by WB and real-time PCR after ILEI overexpression, *p < 0.05, **p < 0.01. J Co-IP showing interactions between ILEI and LIFR in ILEI-overexpressed HK2 cells. K Co-IP showing interactions between ILEI and LIFR in TGF-β1 induced EMT in HK2 cells