Table 1.

rhGH dose in mg/kg/week and IGF-1 Z scores

Participant		Baseline	Week 2	Week 4	Week 8	Week 12
1	IGF-1 Z score	0.8	–	2.6	4.8	2.2
	rhGH dose	0.15	0.3	0.28	0.24a	–
2	IGF-1 Z score	1.0	–	6.0	5.0	3.9
	rhGH dose	0.15	0.28	0.24a	0.16a	–
3	IGF-1 Z score	1.1	–	2.8	4.7	1.7
	rhGH dose	0.14	0.3	0.29	0.24a	–
4	IGF-1 Z score	0.9	–	4.5	1.8	2.9
	rhGH dose	0.16	0.29	0.21a	0.19b	–
5	IGF-1 Z score	2.3	–	4.9	4.2	1.3
	rhGH dose	0.14	0.27	0.22a	0.13a	–
6	IGF-1 Z score	− 1.2	–	1.1	1.3	0.9
	rhGH dose	0.15	0.31	0.33	0.32	–

^aDose reduced due to high IGF-1 levels

^bDose reduced due to crying spells