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Mediation model indicating that CSF P-Tau levels partially mediate the effect of age on hippocampal volume (a, trend), hippocampal atrophy rates (b) and BA35 atrophy rates (c, trend), while correcting for PET β-amyloid levels, in cognitively normal older adults with low β-amyloid levels
#p<0.10; *p<0.05. % indicates the % of the model explained by the mediation. BA=Brodmann Area, CSF=cerebrospinal fluid, p-tau=phospho tau, T Hippo=total hippocampus.
