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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: Mol Immunol. 2021 Dec 23;142:1–10. doi: 10.1016/j.molimm.2021.12.011

Figure 3. Monocytic-MDSCs expressing CD14+ HLA-DRneg/low also express high levels of surface VNN2.

Figure 3.

A) A representative flow cytometry diagram demonstrating 65% VNN2 expression on Mo-MDSCs compared to 8% expression on CD14+ HLA-DRhigh cells (top 10%), relative to their respective isotype controls. B) VNN2 protein expression on Mo-MDSC compared to CD14+ HLA-DRhigh cells (68% vs. 9%, n=4 each, p<0.0004). C) Characteristic cytometry plot demonstrating (CD14+)VNN2high cells express relatively little HLA-DR compared to HLA-DR expression among (CD14+) VNN2low cells. D) Mean HLA-DR expression among the top (10%)-expressing VNN2 cells versus the bottom (10%) of VNN2-expressing cells. E) Representative individual scatter grams of VNN2 and HLA-DR on CD14+ monocytes.