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. Author manuscript; available in PMC: 2022 Sep 15.
Published in final edited form as: Cancer. 2021 Jun 22;127(18):3390–3402. doi: 10.1002/cncr.33660

Table 5.

Performance of asymptomatic surveillance scans by radiographic imaging modality within the LEAD cohort.

Surveillance CT Surveillance PET Surveillance Other Imaging TOTAL
Total Scans 402 160 22 584
Concerning for Relapse 29 (7%) 39 (24%) 0 (0%) 68b (12%)
Total True Positives 8 (2%) 13 (8%) 0 (0%) 21 (4%)
Sensitivity 88% 100% 0% 91%
Specificity 95% 83% 100% 92%
PPV 27% 33% 0% 31%
NPV 99.7% 100% 100% 99.6%

Abbreviations: Concerning for Relapse, radiographic imaging study concerning for relapse as initially read by a radiologist; Total True Positive, imaging study read as positive by radiologist and later confirmed by biopsy or further imaging studies; PET, positron-emission tomography; CT, computed tomography; Other Imaging, includes magnetic resonance imaging and mammography used as part of surveillance for FL; PPV, positive predictive value; NPV, negative predictive value.