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General composition of the mTOR complex 1 and its importance in cellular growth and metabolism. mTOR: mammalian target of rapamycin; RAPTOR: regulatory-associated protein of mTOR; mLST8: mammalian lethal with sec-13 protein-8; DEPTOR: DEP domain-containing mTOR-interacting protein; PRAS40: proline-rich Akt substrate 40 kDa; 4E-BP1: eukaryotic translation initiation factor 4E-binding protein; S6K1: protein S6 kinase 1.
