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. Author manuscript; available in PMC: 2022 Jan 29.
Published in final edited form as: Environ Int. 2021 Sep 2;157:106849. doi: 10.1016/j.envint.2021.106849

Fig. 2. Retrospective temporal molecular phenotyping.

Fig. 2.

(A) The approach we are proposing provides a pathway from external exposures and their metabolites to the molecular architecture of physiology (the ‘building blocks of life’) to the biological response that is invoked when environmental factors interact with our physiology. (B) A subsample of the classes of compounds we have detected in prenatal and postnatal components of teeth to exemplify the categories in panel A. Clusters are generated by chemical similarity between metabolites.