Table 2.
Comparative evaluation of patients with or without orthostatic hypotension.
| Parameters | Patients with OH (n = 12) | Patients without OH (n = 80) | P-value |
|---|---|---|---|
| Age | 56.42 ± 11.54 | 49.78 ± 12.06 | 0.07 |
| Gender (Male) | 7 (58.3%) | 47 (58.7%) | 0.97 |
| Hypertension | 2 (16.6%) | 19 (23.7%) | 0.58 |
| Symptoms during COVID-19 | |||
| Fever | 11 (91.7%) | 52 (65%) | 0.06 |
| Cough | 9 (75%) | 41 (51.2%) | 0.124 |
| Sore throat | 2 (16.7%) | 14 (17.5%) | 0.943 |
| Dyspnea | 6 (50%) | 28 (35%) | 0.31 |
| Chest pain | 2 (16.6%) | 12 (15%) | 0.881 |
| Myalgia | 3 (25%) | 8 (10%) | 0.135 |
| Symptoms post COVID-19 | |||
| Dyspnea | |||
| Cough | 1 (8.3%) | 7 (8.7%) | 0.96 |
| Fatigue | 4 (33.3%) | 7 (8.7%) | 0.01 |
| Palpitations | 5 (41.7%) | 10 (12.5%) | 0.01 |
| Orthostatic intolerance | 8 (66.7%) | 6 (7.5%) | <0.0001 |
| Chest pain | 2 (16.7%) | 12 (15%) | 0.88 |
| Dizziness | 7 (58.3%) | 6 (7.5%) | <0.0001 |
| Syncope | 2 (16.7%) | 0 | 0.0002 |
| Severity | |||
| Asymptomatic | 0 | 12 (15%) | |
| Mild | 3 (25%) | 35 (43.7%) | 0.002 |
| Moderate | 4 (33.3%) | 28 (35%) | |
| Severe | 5 (41.7%) | 5 (6.25%) | |
| HRV (RMSSD) [ms] | 5.3 ± 3.2 | 15.2 ± 12.1 | 0.006 |
| HRV (SDNN) [ms] | 9.2 ± 6.0 | 18.1 ± 13.3 | 0.02 |
| Mean HR | 99.2 ± 17.8 | 86.4 ± 14.1 | 0.006 |
| IL-6(pg/ml) | 36.3 ± 82.2 | 6.7 ± 12.4 | 0.016 |
| CRP(mg/L) | 56.4 ± 109.8 | 15.8 ± 32.4 | 0.03 |
| D-Dimer(μg/L) | 919.9 ± 1283.8 | 453.2 ± 703.6 | 0.11 |
| LDH(U/L) | 373.4 ± 364.8 | 364.8 ± 182.3 | 0.89 |
| Ferritin(μg/L) | 8111.7 ± 25513.3 | 317.2 ± 298.9 | 0.04 |
| Haemoglobin (gm%) | 12.2 ± 2.5 | 12.4 ± 1.6 | 0.81 |
| TLC (per mm3) | 9283.6 + 2927.7 | 9138.1 + 9258.8 | 0.96 |
| LVEF (%) | 61.3 ± 5.7 | 60.5 ± 5.1 | 0.63 |
| Avg signal value (microV) | 0.002 ± 0.006 | 0.001 ± 0.003 | 0.26 |
| Avg RR interval (ms) | 635.9 ± 127.7 | 714.6 ± 111.5 | 0.028 |
Abbreviations: Avg: average; CRP: C-reactive protein; HR: heart rate; HRV: Heart rate variability; IL-6: interleukin-6; LDH: lactate dehydrogenase; LVEF: left ventricular ejection fraction; ms: millisecond; microV: microvolt; OH: orthostatic hypotension; RMSSD: Root Mean Square Standard Deviation; TLC: total leucocyte count.