Table 3.
Divergence of the isolated strains in serial passages in vitro and the Wuhan reference genome in ascending order.
| Strain | Between group mean pairwise distance ( × 10−4) | Substitution rate per year (8-month study period) ( × 10−4) |
|---|---|---|
| A818 | 3.3 | 4.9 |
| B5155 | 3.7 | 5.5 |
| B5845 | 4.0 | 6.0 |
| A893 | 4.3 | 6.4 |
| B4926 | 4.7 | 7.1 |
| A6301 | 4.9 | 7.3 |
| A607 | 5.0 | 7.6 |
| A7326 | 6.0 | 9.0 |
| A4707 | 6.2 | 9.2 |
| A6137 | 7.1 | 10.0 |
The between group mean distance gives the mean number of substitutions per site between the various strain and the reference genome Wuhan-Hu-1 at the end of the serial passages. .