Table 3.
Univariate and Multivariate Predictors of Postoperative AKI
| Factor | Univariate Analysis | Multivariate Analysis | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | |
| Age, yrs | 1.032 | 1.013–1.051 | 0.001 | 1.020 | 1.000–1.041 | 0.049 |
| Diabetes | 1.997 | 1.331–2.996 | 0.001 | 2.315 | 1.451–3.693 | <0.001 |
| Hypertension | 1.684 | 1.192–2.379 | 0.003 | 1.504 | 1.019–2.22 | 0.04 |
| ACEI/ARB | 2.644 | 1.306–5.352 | 0.007 | 2.451 | 1.146–5.240 | 0.021 |
| LVEF, % | 0.981 | 0.962–1.000 | 0.047 | |||
| eGFR, mL/min/1.73m2 | 0.986 | 0.975–0.996 | 0.007 | |||
| Baseline SCr, μmol/L | 1.013 | 1.003–1.023 | 0.011 | |||
| Albumin, g/L | 0.917 | 0.875–0.962 | <0.001 | |||
| Uric acid, μmol/L | 1.002 | 1.001–1.004 | 0.003 | 1.003 | 1.001–1.004 | 0.002 |
| Hemoglobin, g/L | 0.984 | 0.974–0.994 | 0.001 | 0.985 | 0.974–0.995 | 0.004 |
| Fibrinogen, g/L | 1.196 | 1.005–1.423 | 0.044 | |||
| Low T3 syndrome | 1.821 | 1.214–2.730 | 0.004 | 1.609 | 1.033–2.504 | 0.035 |
| Surgery | 0.046 | |||||
| CABG alone | 0.478 | 0.267–0.857 | 0.013 | |||
| Valve alone | 0.624 | 0.371–1.048 | 0.075 | |||
| CABG and valve surgery | Reference | |||||
| Cross-clamp time, min | 1.012 | 1.006–1.018 | <0.001 | |||
| CPB time | 1.010 | 1.006–1.015 | <0.001 | 1.009 | 1.004–1.015 | 0.001 |
Note: Results reported as odds ratio and 95% confidence interval.
Abbreviations: CABG, coronary artery bypass grafting; CPB, cardiopulmonary bypass; eGFR, estimated glomerular filtration rate; SCr, serum creatinine.