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. 2022 Jan 22;2022:4382999. doi: 10.1155/2022/4382999

Figure 1.

Figure 1

Overexpression of miR-325-3p alleviated myocardial fibrosis in rats with PAH. (a) HE staining of the pulmonary artery and quantitative statistics of pulmonary arterial medial wall thickness (%). (b) miR-325-3p expression in myocardial tissue was measured by qRT-PCR. (c) RVSP and RVHI of rats. (d) HE staining of the right ventricle (×100, 100 μm). (e) Masson staining of the right ventricle (×100, 100 μm). (f, g) qRT-PCR and Western blot were performed to measure collagen I, collagen III, MMP2, and MMP9 expressions in heart tissue. ∗P < 0.05 vs. Sham; #P < 0.05 vs. PAH.