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HE4 was negatively correlated with miR-325-3p expression. (a) HE4 expression in right heart tissue was assessed by qRT-PCR. (b) Western blot was used to detect the expression of HE4 in right heart tissue. (c) Pearson correlation coefficient was used to analyze miR-325-3p and HE4, collagen I, collagen III, MMP2, and MMP9 correlation. ∗P < 0.05 vs. Sham; #P < 0.05 vs. PAH.
