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Overexpression of HE4 could reverse the effect of miR-325-3p mimics. (a) qRT-PCR was performed to detect the expression of miR-325-3p and HE4. ∗P < 0.05 vs. NC mimics; #P < 0.05 vs. miR-325-3p mimics+oe-NC. (b) Western blot was used to measure collagen I, collagen III, MMP2, MMP9, PI3K, p-PI3K, AKT, and p-AKT levels. (c) Quantitative statistics of (b) proteins. ∗P < 0.05 vs. NC mimics; #P < 0.05 vs. miR-325-3p mimics+oe-NC.
