表3 SSCI患者与健康体检者TLR4/MyD88/NF-κB基因及相关炎症因子表达比较

Table 3 Expression of TLR4/MyD88/NF-κB pathway genes and related inflammatory factors of SSCI patients and healthy subjects   ( x ± s)

组别	n	TLR4	MyD88	NF-κB	TNF-α(pg/mL)	IL-12(pg/mL)	IL-6(pg/mL)
SSCI患者	105	2.14±0.35	3.18±0.45	2.52±0.37	38.50±4.22	22.13±3.50	3.58±0.64
健康体检者	45	0.95±0.13	1.03±0.16	1.07±0.15	7.61±0.91	5.15±0.84	2.13±0.37
t值	—	22.127	31.166	25.371	48.534	32.093	23.990
P值	—	＜0.01	＜0.01	＜0.01	＜0.01	＜0.01	＜0.01

“—”：无相关数据.SSCI：继发性脊髓损伤；TLR4：Toll样受体4；MyD88：髓样分化因子；NF-κB：核因子-κB；TNF-α：肿瘤坏死因子-α；IL-12：白细胞介素-12；IL-6：白细胞介素-6.