表4 SSCI完全损伤组与不完全损伤组TLR4/MyD88/NF-κB基因及相关炎症因子表达比较
Table 4 Expression of TLR4/MyD88/NF-κB pathway genes and related inflammatory factors of complete and incomplete injury groups of SSCI patients ( x ± s)
|
组别 |
n |
TLR4 |
MyD88 |
NF-κB |
TNF-α(pg/mL) |
IL-12(pg/mL) |
IL-6(pg/mL) |
|
完全损伤组 |
33 |
3.62±0.52 |
5.71±0.80 |
4.13±0.61 |
52.01±7.25 |
30.00±4.59 |
5.84±0.72 |
|
不完全损伤组 |
72 |
1.46±0.27 |
2.02±0.34 |
1.78±0.30 |
32.31±5.80 |
17.15±3.14 |
2.71±0.40 |
|
t值 |
— |
28.042 |
33.260 |
26.523 |
14.907 |
16.735 |
28.674 |
|
P值 |
— |
<0.01 |
<0.01 |
<0.01 |
<0.01 |
<0.01 |
<0.01 |
“—”:无相关数据.SSCI:继发性脊髓损伤;TLR4:Toll样受体4;MyD88:髓样分化因子;NF-κB:核因子-κB;TNF-α:肿瘤坏死因子-α;IL-12:白细胞介素-12;IL-6:白细胞介素-6.