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. 2021 Oct 24;148(2):321–330. doi: 10.1007/s00432-021-03818-w

Table 2.

NCSLC patients EGFR mutation rate and clinical information analysis by NGS

Overall patients Case(n) EGFR Positive rate (%) χ2 (Bray et al. 2018) P
Mutated type Wild type
Sex
 Male 468 141 327 30.1 69.23 0.00
 Female 334 199 135 59.6
Age
 < 45 32 12 20 37.5 12.087 0.13
 45 ~ 59 256 123 133 48.0
 60 ~ 74 379 163 216 43.0
 75 ~ 89 131 42 89 32.1
 > 90 4 0 4 0.0
Sample type
 Tumor tissue 442 206 236 46.6 24.109 0.00
 Metastatic tissue 3 1 2 33.3
 Cytology 49 31 18 63.3
 Sputum 8 4 4 50.0
 Blood 300 98 202 32.7