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. 2022 Jan 29;54:7. doi: 10.1186/s12711-022-00699-6

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Non-metric multidimensional scaling representations and heatmaps comparing caecal microbiota composition between lines N and 6₁. Non-metric multidimensional scaling representations of the OTU composition of caecal contents using the Bray–Curtis dissimilarity. Comparison of composition between lines N and 6₁ in Experiment 1 (a) and Experiment 2 (b). A significant difference in microbiota composition is observed between lines after correction for isolator and sex effects (Permanova, P < 0.001). Heatmaps of the caecal OTU with differential abundances between lines N (in blue) and 6₁ (in red) in Experiment 1 (c) and in Experiment 2 (d)