Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jan 29;20:56. doi: 10.1186/s12951-022-01245-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 4 — Exo-Gel promoted proliferation and migration of chondrocytes in vitro. A In vitro investigate the effect of conditioned medium after Exo-Gel incubation for 1 week on proliferation and migration of chondrocytes by co-culture. B The cell viability of chondrocytes examined by CCK-8 analysis. Data are expressed as means ± SEM (n = 6). *p < 0.05, Exo-Gel compared to Gel group. C Proliferation of chondrocytes was confirmed by EDU kit assay (bar = 100 μm). D Quantification of rate of EDU positive cells in C was performed. Data are expressed as means ± SEM (n = 8). (E) Transwell assay to show a representative image of migrating chondrocytes (bar = 200 μm). F Quantitative analysis of migrating cells in E. Data are expressed as means ± SEM (n = 6). G A representative image showing the migration ability of chondrocytes by the scratch test (bar = 500 μm). H Quantitative analysis of chondrocyte migration rate (G). Data are expressed as means ± SEM (n = 6). *p< 0.05