. 2021 Nov 29;10(1):e1820. doi: 10.1002/mgg3.1820

TABLE 3.

In silico analysis of identified variant in WT1 gene

Gene	Mutation type	cDNA Change ^a	Protein change	Minor allele frequency ^b			Functional prediction ^c
Gene	Mutation type	cDNA Change ^a	Protein change	1KG	ExAC	gnomAD	DANN	MutationTaster	CADD
WT1	Heterozygous	c. C1387T	p.R463*	0	0	0.000006583	Damaging	Damaging	14.003

^{^a}

The GenBank accession number of WT1 is NM_024426.4.

^{^b}

Allele frequencies were estimated according to the 1KG Project, ExAC, and gnomAD databases.

^{^c}

Mutation assessment using MutationTaster and CADD tools. High CADD scores suggest that a variant is likely to have deleterious effects. The CADD cutoff is usually set at 4.