Table 3.
Cohort | Completed DRA-OPAT | Did Not Complete Program |
---|---|---|
N | 16 | 19 |
Age, years (median, IQI) | 35 (28–53.3) | 40 (34–49) |
Male, N (%) | 9 (56.3) | 10 (52.6) |
Race, non-white | 1 (6.3) | 5 (26.3) |
Cocaine use | 1 (6.3) | 1 (5.3) |
Opioid use | 15 (93.8) | 13 (68.4) |
Polysubstance use | 8 (50) | 14 (73.7) |
Stimulant use | 8 (50) | 15 (78.9) |
Medication for opioid use disordera | 14 (87.5) | 8 (42.1) |
Homelessa | 12 (75) | 8 (42.1) |
Insured | 1 (6.3) | 6 (31.6) |
Charlson comorbidity index | 32 (12.5) | 20 (12–33) |
HIV | 0 (0) | 0 (0) |
Hepatitis C | 4 (25) | 5 (26.3) |
Cerebrovascular disease | 1 (6.3) | 2 (10.5) |
Congestive heart failure | 0 (0) | 4 (21.1) |
Diabetes mellitus | 2 (12.5) | 5 (26.3) |
Hepatic disease | 5 (31.3) | 7 (36.8) |
Chronic pulmonary disease | 6 (37.5) | 6 (31.6) |
Kidney disease | 2 (12.5) | 2 (10.5) |
Endocarditis | 7 (43.8) | 7 (36.8) |
Osteoarticular infection | 6 (37.5) | 8 (42.1) |
Skin/soft tissue infection | 12 (75) | 8 (42.1) |
Vertebral abscess/discitis/osteomyelitis | 6 (37.5) | 4 (21.1) |
Staphylococcus aureus bacteremia | 8 (50) | 9 (47.4) |
Bone or joint debridement | 7 (43.8) | 5 (26.3) |
Cardiac valve replacement | 0 (0) | 0 (0) |
Soft tissue debridement | 6 (37.5) | 7 (36.8) |
Spinal debridement | 2 (12.5) | 1 (5.3) |
Hospital length of stay, days (median, IQI)a | 13.5 (10.6–18.5) | 9.1 (7.7–13.4) |
Days at program facilitya | 24 (19.5–38) | 4 (2–9) |
30-day readmission | 2 (12.5) | 2 (10.5) |
90-day readmission | 5 (31.3) | 4 (21.1) |
Mortality, 30-day all-cause | 0 (0) | 0 (0) |
Mortality, 1-year | 0 (0) | 0 (0) |
Positive toxicology screen during program | 0 (0) | 2 (10.5) |
PICC line abuse | 0 (0) | 2 (10.5) |
Adverse event during program treatment | 3 (18.8) | 4 (21.1) |
Abbreviations: DRA-OPAT, drug recovery assistance and parenteral antibiotic therapy; HIV, human immunodeficiency virus; IQI, 25%–75% interquartile interval; PICC, peripherally inserted central venous catheter.
Significant at P < .05.