Table 2.
Genotypic Carbapenemase Targets Identified in Phenotypically Carbapenemase Positive Isolates
| Primary Algorithm Criterion: Imipenem- or Meropenem-R Plus Ceftazidime-NS Plus Cefepime-NS |
Primary Algorithm Criterion OR Secondary Algorithm Criterion: Imipenem- or Meropenem-R Plus Ceftazidime-NS Plus Cefepime-NS (Algorithm) OR Imipenem- or Meropenem-R Plus Ceftolozane/Tazobactam-NS |
|||
|---|---|---|---|---|
| Genotypic Target | True Positive | False Negative | True Positive | False Negative |
| VIM | 130 | 6 | 134 | 2 |
| IMP | 15 | 0 | 15 | 0 |
| NDM | 13 | 0 | 13 | 0 |
| KPC | 7 | 1 | 7 | 1 |
| GES | 31 | 13 | 43 | 1 |
| VIM and IMP | 3 | 0 | 3 | 0 |
| VIM and OXA | 1 | 0 | 1 | 0 |
| VIM and KPC | 8 | 0 | 8 | 0 |
| No targets identified | 17 | 20 | 20 | 17 |
Abbreviations: GES, Guiana extended spectrum; IMP, imipenemase; KPC, Klebsiella pneumoniae carbapenemase; NDM, New Delhi metallo-beta-lactamase; NS, nonsusceptible; OXA, oxacillinase; R, resistant; VIM, Verona integron-encoded metallo-β-lactamase.