Table 2.

Univariate and multivariate analyses for factors influencing overall survival (OS) of lung adenocarcinoma patients in the TCGA database.

Variables		Overall survival (OS)
		Univariate		Multivariate
		HR (95% CI)	P-value	HR (95% CI)	P-value
Group (low risk)		0.3519 (0.2467–0.5019)	<0.001***	–	–
LARSO		26,401 (1,640–424,906)	<0.001***	1,867.458 (8.299–42,020)	0.00642**
Stage	Stage II	2.472 (1.718–3.557)	<0.001***	–	–
	Stage III	3.494 (2.383–5.124)	<0.001***	–	–
	Stage IV	3.817 (2.199–6.624)	<0.001***	–	–
T	T2	1.452 (1.017~2.073)	0.0398*	–	–
	T3	2.958 (1.758–4.979)	<0.001***	2.644 (1.266–5.515)	0.00963**
	T4	2.914 (1.501–5.659)	0.00159**	–	–
N (N0)		0.388 (0.288–0.521)	<0.001***	–	–
M (M1)		2.133 (1.245–3.654)	0.00583**	–	–

All results were calculated by the survival package of R 4.0.2 software.

TCGA, The Cancer Genome Atlas; CI, confidence interval; LARSO, lncRNA-associated risk score of overall survival. *P < 0.05, **P < 0.01, ***P < 0.001.