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. 2022 Jan 17;12:791399. doi: 10.3389/fimmu.2021.791399

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Copyright © 2022 Piekarska, Radwan, Tarnowska, Wiśniewski, Krasiński, Radwan, Wilczyński, Malinowski and Nowak

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Concentration of soluble HLA-G per milliliter of plasma (IU/ml) measured in semen samples of G-C-ins haplotype carriers. Haplotype was estimated in the following order: rs1632947:−964G>A; rs1233334:−725G>C/T; rs371194629:insATTTGTTCATGCCT/del. Blue box represents the level of sHLA-G measured in normozoospermic men, green box – in men with asthenozoospermia, red box – in men with teratozoospermia. Boxes are drawn from the first quartile (25th Percentile) to the third quartile (75th Percentile). Black lines in boxes are medians. Whiskers represent 10-90 percentiles. N is the number of patients. P-values are calculated by Mann-Whitney test.