Table 3.
The level of secreted HLA-G in semen dependent on the haplotype/diplotype in normozoospermic men and men with sperm abnormalities.
| Haplotype/diplotype* | Normozoospermia | Abnormal sperm | ||
|---|---|---|---|---|
| N | median [IU/mL] | N | median [IU/mL] | |
| ATdel | 2 | 847.1 | 1 | 594.9 |
| ACdel | 22 | 574.1 | 47 | 650.0 |
| ACins | 23 | 391.2 | 50 | 261.7 |
| GCdel | 25 | 347.7 | 47 | 351.5 |
| AGdel | 12 | 315.2 | 5 | 395.3 |
| GGdel | 7 | 145.9 | 21 | 200.7 |
| GCins | 28 | 80.8 | 70 | 67.5 |
| GTins | 1 | 31.3 | 3 | 178.8 |
| ACdel/ACdel | 6 | 1 047.0 | 16 | 743.4 |
| ACins/ATdel | 2 | 847.1 | 1 | 594.9 |
| ACins/GCdel | 13 | 720.1 | 29 | 495.9 |
| AGdel/AGdel | 2 | 582.2 | 0 | – |
| ACdel/GCdel | 2 | 537.9 | 6 | 459.4 |
| ACdel/AGdel | 8 | 315.2 | 5 | 395.3 |
| GCdel/GCdel | 1 | 160.6 | 1 | 91.1 |
| GGdel/ACins | 7 | 145.9 | 17 | 99.8 |
| GCdel/GCins | 8 | 112.5 | 10 | 149.7 |
| GCins/GCins | 10 | 75.7 | 30 | 59.6 |
| GTins/ACins | 1 | 31.3 | 3 | 178.8 |
| ACdel/GGdel | 0 | – | 4 | 282.8 |
*Haplotypes/diplotypes were estimated in the following order: rs1632947:-964G>A; rs1233334:-725G>C/T; rs371194629:insATTTGTTCATGCCT/del. Normozoospermia – total number of sperm cells, their concentration, progressive motility and morphology above or equal reference values; Men with abnormal sperm – men with at least one parameter of semen below reference value.