Figure 3.

Differential expression of mRNAs in the case and control groups. (A) The Venn diagram shows 23 upregulated mRNAs and 47 downregulated mRNAs in the case group, and 16,767 mRNAs are maintained. (B) The differentially expressed mRNAs between the case and control groups are described using volcano plots. The red points represent the differentially expressed mRNAs on the statistical criteria of fold change >2-fold upregulated (log2 scaled) and P < 0.05 (−log10 scaled); the green points represent the differentially expressed mRNAs on the statistical criteria of fold change <1/2 downregulated (log2 scaled) and P < 0.05 (−log10 scaled). (C) Hierarchical clustering analysis of the 23 upregulated and 47 downregulated mRNAs.