Table 2.
Results of the six SNPs in the GWAS database.
| Number | SNPs | mRNA | Chr | Alleles | Cases (N=155) | Controls (N=141) | MAF (Cases) | MAF (Controls) | OR (95%CI) a | P |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | rs2291236 | BASP1 | chr5:17228908 | C>T | 88/57/10 | 103/33/5 | 0.248 | 0.152 | 2.26 (1.34-3.80) | 0.002 |
| 2 | rs2962375 | BASP1 | chr5:17226471 | A>T | 70/68/17 | 49/78/14 | 0.329 | 0.376 | 0.52 (0.32-0.84) | 0.007 |
| 3 | rs7736442 | BASP1 | chr5:17241405 | C>T | 78/60/17 | 87/47/7 | 0.303 | 0.216 | 2.01 (1.25-3.23) | 0.004 |
| 4 | rs9273410 | HLA-DQB1 | chr6:32627250 | C>A | 41/78/36 | 51/68/22 | 0.484 | 0.397 | 1.44 (1.03-2.01) | 0.035 |
| 5 | rs2965298 | R3HDM4 | chr19:90372 | G>A | 59/75/21 | 51/62/28 | 0.377 | 0.418 | 0.60 (0.36-0.99) | 0.045 |
| 6 | rs924150 | TSHZ3 | chr19:31829903 | A>C | 41/82/32 | 54/64/23 | 0.471 | 0.390 | 1.88 (1.21-2.91) | 0.005 |
a
Logistic regression analysis adjusted for age, sex, years of silica dust exposure and smoking status in the additive model (OR; CI).