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. 2022 Jan 17;12:766956. doi: 10.3389/fneur.2021.766956

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Copyright © 2022 Bsteh, Hegen, Riedl, Altmann, Di Pauli, Ehling, Zulehner, Rommer, Leutmezer, Deisenhammer and Berger.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Probability of clinical disease reactivation in and after pregnancy stratified according to the Vienna Innsbruck Pregnancy Risk in Multiple Sclerosis (VIPRiMS) score in the generation cohort (A,B) and in the validation cohort (C,D). Vertical dotted line marks the timepoint of delivery. Horizontal dotted lines indicate the 10th and 50th percentile of probability of clinical disease reactivation. Groups significantly differed in all the four graphs (p < 0.001, calculated by log-rank test for trend).