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Agrin silencing prohibited NSCLC cell growth, and alleviated IL-6, p-AKT and Foxp3 expression in vivo. (A–F) Agrin knockdown suppressed NSCLC cell growth in the xenograft tumor model of BALB/C nude mice with or without PBMC injection. (G, H) Representative images of Ki67, Foxp3, p-AKT, CD8, Agrin and IL-6 staining in the tumor tissues. The images were taken at 200X magnification. Scale bar, 50 μm. N ≥ 4; *P < 0.05.
