TABLE 1.
Anticancer activity of compounds (µM) (2a-2j).
| Compounds | MCF-7 cell line | ||
|---|---|---|---|
| GI50 (µM) | TGI (µM) | LC50 (µM) | |
| 2a | 03.3 ± 0.23 | 07.3 ± 1.15 | 07.5 ± 0.03 |
| 2b | 0.05 ± 0.15 | 0.65 ± 2.45 | 0.89 ± 0.28 |
| 2c | 0.20 ± 0.82 | 0.50 ± 1.50 | 0.75 ± 0.35 |
| 2d | 0.10 ± 0.74 | 0.70 ± 0.68 | 1.50 ± 1.40 |
| 2e | 0.05 ± 0.33 | 0.06 ± 1.32 | 0.79 ± 1.25 |
| 2f | 0.65 ± 0.10 | 11.0 ± 1.62 | 20.3 ± 0.24 |
| 2g | 0.43 ± 0.90 | 0.75 ± 1.53 | 15.6 ± 0.72 |
| 2h | 0.02 ± 0.24 | 0.15 ± 0.19 | 0.72 ± 0.31 |
| 2i | 0.07 ± 0.56 | 0.60 ± 0.41 | 2.25 ± 0.31 |
| 2j | 0.04 ± 0.50 | 0.29 ± 0.72 | 9.12 ± 1.21 |
| Doxorubicin | 0.04 ± 0.75 | 0.25 ± 0.23 | 0.80 ± 0.46 |
Data represent the mean ± standard deviation (SD) of the mean values of three separate experiments.