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. 2022 Jan 17;9:796599. doi: 10.3389/fchem.2021.796599

TABLE 1.

Anticancer activity of compounds (µM) (2a-2j).

Compounds MCF-7 cell line
GI50 (µM) TGI (µM) LC50 (µM)
2a 03.3 ± 0.23 07.3 ± 1.15 07.5 ± 0.03
2b 0.05 ± 0.15 0.65 ± 2.45 0.89 ± 0.28
2c 0.20 ± 0.82 0.50 ± 1.50 0.75 ± 0.35
2d 0.10 ± 0.74 0.70 ± 0.68 1.50 ± 1.40
2e 0.05 ± 0.33 0.06 ± 1.32 0.79 ± 1.25
2f 0.65 ± 0.10 11.0 ± 1.62 20.3 ± 0.24
2g 0.43 ± 0.90 0.75 ± 1.53 15.6 ± 0.72
2h 0.02 ± 0.24 0.15 ± 0.19 0.72 ± 0.31
2i 0.07 ± 0.56 0.60 ± 0.41 2.25 ± 0.31
2j 0.04 ± 0.50 0.29 ± 0.72 9.12 ± 1.21
Doxorubicin 0.04 ± 0.75 0.25 ± 0.23 0.80 ± 0.46

Data represent the mean ± standard deviation (SD) of the mean values of three separate experiments.