Figure 3.

Trial- and neoadjuvant treatment arm-level correlations between median PFS and median OS. (A) Trial-level correlation between Δ median PFS and Δ median OS. Δ median survival time is defined as the absolute difference between the median survival of treatment arm and the median survival of standard arm. (B) Neoadjuvant treatment arm-level correlation between median PFS and median OS. Circle size is proportional to the number of patients in each arm. The solid blue line indicates the fitted weighted linear regression line; the light green zone represents its 95% CI; r indicates the correlation coefficient. PFS, progression-free survival; OS, overall survival; CI, confidence interval.