Table 1.
Summary table of tests performed by cohorts.
| Test |
Cohort 1
(n = 12/group) |
Cohort 2
(n = 12/group) |
Cohort 3
(n = 12/group) |
Cohort 4
(n = 10/group) |
Cohort 5
(n = 12/group) |
Cohort 6
(n = 11/group) |
Cohort 7
(n = 12/group) |
|---|---|---|---|---|---|---|---|
| General observations | Body weight EAE scoring |
Body weight EAE scoring |
|||||
| Motor | Rotarod Open field Grip test |
Rotarod Open field Grip test |
Grid test | Grid test | - | ||
| Sensitive | – | Acetone facial | Von Frey pharmaco Hotplate Acetone paw test |
Von Frey Chaplan Hotplate Acetone paw test |
Von Frey Chaplan Paintbrush test Air puff |
Acetone facial Paintbrush test Air puff |
Hotplate pharmaco |
| Cognitive | Object recognition Social interaction |
Object recognition EPM Marble burying Y-maze |
Y-maze EPM Marble burying |
– | – | Social interaction | - |
Body weight, Experimental Autoimmune Encephalomyelitis (EAE) scoring, and von Frey Chaplan were determined in all seven cohorts. Here we show data from only two cohorts closely representative of the others.