TABLE 1.

Demographic Data

			Patients abstaining from alcohol at:
Characteristic	Controls	Alcohol-dependent patients at baseline	2-mo follow-up	6-mo follow-up
No. of patients	32	16	10	8
Age (y)	45 ± 13	45 ± 8	46 ± 8	44 ± 8
No. of women/men	14/18	3/13	3/7	2/6
Alcohol craving (DAQ scores)
Desire and intention		16 ± 7	9 ± 4	10 ± 4
Negative reinforcement		14 ± 7	6 ± 3	9 ± 7
Control		5 ± 3	4 ± 3	7 ± 5
Alcohol consumption parameters
Reported alcohol use (y)	26.6 ± 8.1	26.5 ± 12.9
Abstinence (d)	5.8 ± 6.6*	7 ± 4†	56 ± 12*,‡	101 ± 20*,§
No. of drinks/wk (TLFB)	2.4 ± 2.1	133 (124–184)‖	1 (0–4.1)‡,‖	6 (1–8)§,‖
No. of drinks/drinking day (TLFB)		19 (18–26)‖	2 (0–10)‡,‖	5 (3–10)§,‖
hEtG (pg/mg)	8.1 (5.3–17.5)‖,¶	221 (143–486)‖,#	51 (9–118)‡,‖	61 (30–76)§,‖
18F-FPEB imaging
Injected dose (MBq)	177 ± 7	175 ± 11	174 ± 7	174 ± 5
Specific activity (MBq/nmol)	90 ± 52	97 ± 51	81 ± 38	140 ± 67
Injected mass (μg)	0.63 ± 0.60	0.56 ± 0.43	0.58 ± 0.24	0.34 ± 0.18

^*Self-reported.

^†Medically supervised.

^‡Interval from baseline to 2 mo.

^§Interval from 2 to 6 mo.

^‖Continuous data are reported as median, with interquartile range in parentheses.

^¶n = 29 (3 controls refused hair sampling).

^#n = 14 (2 alcohol-dependent patients refused hair sampling).

DAQ = Desire for Alcohol Questionnaire; TLFB = timeline follow-back method; hEtG = hair ethyl glucuronide.

Continuous data are reported as mean ± SD unless otherwise indicated.